Discover a solution designed with your early to moderate presbyopic patients’ needs in mind. Qlosi™ offers an alternative that combines proven efficacy, trusted safety, and lasting comfort with a flexible dosing schedule of 1 to 2 doses in each eye per day—an approach unlike any other.
With Qlosi™, your early to moderate presbyopic patients can enjoy a break from their readers, enhanced comfort, and fewer compromises—bringing clarity and ease together.
The condition makes everyday tasks like reading a menu or checking a phone screen a constant hassle.
Presbyopia often appears as one of the first signs of aging. Qlosi™ is designed specifically for adults with early to moderate presbyopia who want an effective, discreet, and modern solution.
Adults who don’t need glasses for distance (-0.75 D to +0.50 D) but rely on readers (up to +2.00 D) for near tasks.
Adults who wear contact lenses and face challenges with close-up tasks and depend on low-power readers (+2.00 D or less).
Adults with mild farsightedness (+0.25 D to +1.25 D) looking for a simple way to manage their near vision changes.
Explore why Qlosi™ is the reliable near vision enhancement redefining presbyopia care.
Clinical data from Day 8 and Day 15 demonstrates how Qlosi’s formulation delivers efficacy and comfort in a flexible way, ensuring patients can achieve significant near vision improvements with the freedom to take a second dose as needed.
Whether for a busy workday or a special evening out, Qlosi adapts to their lifestyle while minimizing side effects like discomfort or dimming.
Primary endpoint: 40.1% of Patients achieved ≥ 3-line improvement in DCNVA, and no loss of 1-line or more in distance visual acuity (Study Eye) on Day 8 at 1-hour post-dose 1 which was significantly greater (P < 0.0001) than that of the vehicle group (19.1%). Qlosi (n=309) and Vehicle (n=304).
Data from a pooled analysis of two Phase 3, randomized, double-masked, vehicle-controlled clinical studies, NEAR-1 and NEAR-2, Participants (n=613) aged 45 to 64 years old with presbyopia were randomized to either QLOSI n=309 or placebo (n=304) in these two studies and treated for 2 weeks. The primary endpoint of the study was a comparison of the number of participants demonstrating a gain from baseline of 3 lines or more (>= 15 letters) in BDCVA at 40 centimeters without a loss of 1 line or more (>= 5 letters) in BDCVA at 4 meters.
Discover why optometrists and ophthalmologists nationwide are excited about Qlosi™ as a breakthrough solution for patients seeking freedom to see close up.
"Our patients live different lives. And it’s really important for us to have an option that fits the flexibility of their lifestyle as well.”
Optometrist
"What is great about Qlosi is that it can give patients another option to help enhance their near vision and reduce their dependency on glasses or other corrective lenses.”
Optometrist
"We've only been really able to treat presbyopia through prosthetic devices—contact lenses or glasses— or surgery. Qlosi really presents a brand new aspect of eye care.”
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QlosiTM is indicated for the treatment of presbyopia in adults.
Contraindications
Hypersensitivity
Warnings and Precautions
Advise patients to not drive or operate machinery if vision is not clear (e.g., blurred vision). Exercise caution in night driving and other hazardous occupations in poor illumination.
Rare cases of retinal detachment have been reported with miotics. Examination of the retina is advised in all patients prior to initiation of therapy.
Advise patients to seek immediate medical care with sudden onset of flashes of lights, floaters, or vision loss.
QlosiTM is not recommended to be used when iritis is present.
QlosiTM should not be administered while wearing contact lenses. Remove lenses prior to the installation of QlosiTM and wait 10 minutes before reinsertion.
Avoid touching the tip of the vial to the eye or any other surface.
Adverse Reactions
The most common adverse reactions (5% to 8%) are instillation site pain and headaches.
For more information, see the full Prescribing Information.